Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487918 | 0.75 | KMT2A (0.36) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4004452 | 0.70 | HAVCR2 (0.39) | TSHRSMN1; SMN2HTR2CHTR2B | |
| SCHEMBL18711468 | 0.69 | L3MBTL1 (0.38) | SMN1; SMN2L3MBTL1HTR2CHTR2BALDH1A1 | |
| SCHEMBL4003319 | 0.67 | KDM4C (0.41) | HTR2CHTR2BKMT2AKDM4E | |
| SCHEMBL2236478 | 0.67 | TSHR (0.63) | TSHRSMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL18701564 | 0.66 | USP2 (0.41) | TSHRSMN1; SMN2L3MBTL1HTR2CHTR2B | |
| SCHEMBL30324511 | 0.66 | HTR2C (0.33) | HTR2CHTR2BKMT2AMEN1KDM4E | |
| SCHEMBL9511125 | 0.65 | BCHE (0.69) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL15739828 | 0.64 | PDE10A (0.38) | HTR2CHTR2B | |
| SCHEMBL3999675 | 0.63 | GSK3B (0.43) | TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950871-B | 2-substituted-4-arylamino pyrazolotriazine derivative and application thereof in preparing antitumor drugs | 陕西师范大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110950871-A | 2-substituted-4-arylamino pyrazolotriazine derivative and application thereof in preparing antitumor drugs | 陕西师范大学 | 2020-04-03 | — | — | CN | disclosed |