Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.40 |
| ▸ | KLK1 | P06870 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880811 | 0.85 | ATM (0.42) | ATMCYP11B1CYP11B2KLKB1KLK1 | |
| SCHEMBL16881201 | 0.79 | CYP11B1 (0.39) | ATMCYP11B1CYP11B2KLKB1KLK1 | |
| SCHEMBL2008389 | 0.79 | ATM (0.66) | ATMCYP11B1CYP11B2ALDH1A1CYP4A11 | |
| SCHEMBL16881118 | 0.79 | LOXL2 (0.59) | ATMCYP11B1CYP11B2KLKB1KLK1 | |
| SCHEMBL30675668 | 0.79 | ATM (0.50) | ATMCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL26961945 | 0.79 | ATM (0.50) | ATMCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL23120562 | 0.78 | ATM (0.53) | ATMCYP11B1CYP11B2KLKB1KLK1 | |
| SCHEMBL29695095 | 0.76 | MAPK1 (0.61) | ATMALDH1A1CYP4A11CYP4F2LOXL2 | |
| SCHEMBL204895 | 0.76 | MAPK1 (0.61) | ATMALDH1A1CYP4A11CYP4F2LOXL2 | |
| SCHEMBL16880411 | 0.76 | CYP11B1 (0.40) | ATMCYP11B1CYP11B2KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |