Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.41 |
| ▸ | KLK1 | P06870 | 12/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880997 | 0.88 | KMT2A (0.47) | KLKB1KLK1CYP11B1CYP11B2NPSR1 | |
| SCHEMBL16880649 | 0.87 | KMT2A (0.47) | ATMKLKB1KLK1POLB | |
| SCHEMBL28375244 | 0.85 | ATM (0.49) | ATMKLKB1KLK1CYP11B1CYP11B2 | |
| SCHEMBL16880998 | 0.80 | SMN1; SMN2 (0.51) | ATMPOLB | |
| SCHEMBL16880702 | 0.78 | MAPK1 (0.54) | POLBNPSR1 | |
| SCHEMBL16880761 | 0.77 | KLKB1 (0.38) | KLKB1KLK1POLBNPSR1 | |
| SCHEMBL16881190 | 0.77 | ATM (0.42) | ATMKLKB1KLK1CYP11B1CYP11B2 | |
| SCHEMBL16880735 | 0.76 | KLKB1 (0.48) | ATMKLKB1KLK1CYP11B1CYP11B2 | |
| SCHEMBL16881201 | 0.76 | CYP11B1 (0.39) | ATMKLKB1KLK1CYP11B1CYP11B2 | |
| SCHEMBL16881413 | 0.75 | ATM (0.43) | ATMKLKB1KLK1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| EP-3089746-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2016-11-09 | — | — | EP | disclosed |
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |