Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695095 | 1.00 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL15878323 | 0.86 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL4209119 | 0.86 | MAPK1 (0.47) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1441132 | 0.86 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL480126 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL14548780 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL880698 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1439028 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL17298235 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL198840 | 0.84 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117183511-B | Silk-screen printing non-woven fabric and processing technology thereof | 无锡爱勒普科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117183511-A | Silk-screen printing non-woven fabric and processing technology thereof | 无锡爱勒普科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-113649055-B | Catalyst for selective hydrogenation of methyl picolinate and preparation method and application thereof | 湖北大学 | 2023-03-24 | — | — | CN | claimed |
| CN-114773352-A | Process for preparing substituted nicotinamides | 上海赛默罗生物科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-113649055-A | Catalyst for selective hydrogenation of methyl picolinate and preparation method and application thereof | 湖北大学 | 2021-11-16 | — | — | CN | claimed |
| US-7842813-B2 | for synthesis of erythromycin derivatives; reacting thionyl chloride with 6-hydroxylmethyl-nicotinic acid methyl ester to provide 6-chloromethyl-nicotinic acid methyl ester, chlorinating, reacting with ammonia or ammonium hydroxide, sulfiding | ENANTA PHARMACEUTICALS, INC. (US) | 2010-11-30 | — | — | US | claimed |
| WO-2009137739-A1 | PROCESSES FOR THE PREPARATION OF O-[5-[4-AMINO-THIAZOL-2-YL]-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | claimed |
| US-20090281324-A1 | PROCESSES FOR THE PREPARATION OF O-[5-(4-AMINO-THIAZOL-2-YL)-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE | ENANTA PHARMACEUTICALS, INC. | 2009-11-12 | — | — | US | claimed |
| US-12637468-B2 | Substituted [1,2,4]triazolo[4,3-b]pyridazines as GABAA receptor modulators | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2026-05-26 | — | — | US | disclosed |
| US-20260102395-A1 | INHIBITING HISTONE DEACETYLASE 6 | EIKONIZO THERAPEUTICS, INC. (US) | 2026-04-16 | — | — | US | disclosed |
| US-12590084-B2 | Oxadiazole HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20260055090-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2026-02-26 | — | — | US | disclosed |
| US-12492183-B2 | Tetrahydroquinazoline derivatives as selective cytotoxic agents | MERCK SHARP & DOHME LLC (US) | 2025-12-09 | — | — | US | disclosed |
| EP-0332332-B1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5130379-A | Anticholesterol agents and antidiabetic agents | PFIZER INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5036079-A | Anticholesterol | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1989008651-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332332-A1 | Hypoglycemic thiazolidinedione derivatives | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12492183-B2 | Tetrahydroquinazoline derivatives as selective cytotoxic agents | ACIN1, CD4, NFATC1 | MAPK1 741/4885KDM4E 3846/4885L3MBTL1 1393/4885 |
| US-20090281324-A1 | PROCESSES FOR THE PREPARATION OF O-[5-(4-AMINO-THIAZOL-2-YL)-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE | THOP1, HPD, TH | MAPK1 959/4885KDM4E 2039/4885L3MBTL1 4612/4885 |
| US-12590084-B2 | Oxadiazole HDAC6 inhibitors and uses thereof | HDAC6, HDAC1, HDAC9 | MAPK1 919/4885KDM4E 1491/4885L3MBTL1 2432/4885 |
| US-12637468-B2 | Substituted [1,2,4]triazolo[4,3-b]pyridazines as GABAA receptor modulators | GABRA6, GABRA1, GABRB1 | MAPK1 2422/4885KDM4E 3564/4885L3MBTL1 4704/4885 |
| US-20260055090-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, CTTN | MAPK1 587/4885KDM4E 3413/4885L3MBTL1 3673/4885 |
| US-20260102395-A1 | INHIBITING HISTONE DEACETYLASE 6 | HDAC6, HDAC1, HDAC8 | MAPK1 2091/4885KDM4E 866/4885L3MBTL1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.