Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624212 | 1.00 | HSD11B1 (0.47) | HSD11B1IKBKBPIM1PIM2METAP1 | |
| SCHEMBL624211 | 1.00 | HSD11B1 (0.47) | HSD11B1IKBKBPIM1PIM2METAP1 | |
| Valeric Acid SCHEMBL29209782 | 0.83 | FFAR1 (0.39) | HSD11B1IKBKBALDH1A1TDP1MAPT | |
| SCHEMBL28885464 | 0.83 | PIM1 (0.44) | PIM1PIM2NAT1NPC1PARP1 | |
| SCHEMBL625684 | 0.83 | CYP2C9 (0.47) | HSD11B1METAP1NAT1ALDH1A1TDP1 | |
| SCHEMBL28885466 | 0.83 | PIM1 (0.44) | PIM1PIM2NAT1NPC1PARP1 | |
| SCHEMBL625347 | 0.83 | KMT2A (0.45) | PIM1PIM2NPC1TDP1PARP1 | |
| SCHEMBL625348 | 0.83 | KMT2A (0.45) | PIM1PIM2NPC1TDP1PARP1 | |
| SCHEMBL625683 | 0.83 | CYP2C9 (0.47) | HSD11B1METAP1NAT1ALDH1A1TDP1 | |
| SCHEMBL28371952 | 0.83 | KMT2A (0.45) | PIM1PIM2NPC1TDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878095-B | Curcumin bifunctional molecule and preparation method and application thereof | 中山大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-110878095-A | Curcumin bifunctional molecule and preparation method and application thereof | 中山大学 | 2020-03-13 | — | — | CN | disclosed |