Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625683 | 1.00 | CYP2C9 (0.47) | CYP2C9CYP1A2CYP3A4ALDH1A1HPGD | |
| SCHEMBL28885464 | 0.83 | PIM1 (0.44) | F3GSK3BRAB9ANAT1MAOA | |
| SCHEMBL625347 | 0.83 | KMT2A (0.45) | KMT2AMEN1TDP1RAB9AMAOA | |
| SCHEMBL28371952 | 0.83 | KMT2A (0.45) | KMT2AMEN1TDP1RAB9AMAOA | |
| SCHEMBL624211 | 0.83 | HSD11B1 (0.47) | ALDH1A1KMT2AMEN1HSD11B1TDP1 | |
| SCHEMBL28885466 | 0.83 | PIM1 (0.44) | F3GSK3BRAB9ANAT1MAOA | |
| SCHEMBL625348 | 0.83 | KMT2A (0.45) | KMT2AMEN1TDP1RAB9AMAOA | |
| SCHEMBL624212 | 0.83 | HSD11B1 (0.47) | ALDH1A1KMT2AMEN1HSD11B1TDP1 | |
| SCHEMBL28375460 | 0.83 | HSD11B1 (0.47) | ALDH1A1KMT2AMEN1HSD11B1TDP1 | |
| SCHEMBL28588098 | 0.83 | CYP1A2 (0.44) | CYP1A2ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |