SCHEMBL28375659

SCHEMBL28375659

OCCCc1c[nH]c(CCCO)n1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
RAD52 P43351 1/20 0.36
PKM P14618 1/20 0.33
JAK2 O60674 1/20 0.30
ROCK2 O75116 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4266482 0.83 PKM (0.32) PKM
SCHEMBL3468398 0.82 CYP4F2 (0.31)
SCHEMBL8435155 0.81 HRH3 (0.42) ALDH1A1PKM
SCHEMBL3840247 0.79 HRH3 (0.42) ALDH1A1PKM
SCHEMBL8682185 0.78 GPR84 (0.42) ALDH1A1PKM
SCHEMBL5186754 0.78 GPR84 (0.42) ALDH1A1PKM
SCHEMBL31273830 0.78 KCNH2 (0.44) ALDH1A1PKM
SCHEMBL29077364 0.78 KCNH2 (0.44) ALDH1A1PKM
SCHEMBL7850217 0.78 KDM4E (0.33) ALDH1A1
SCHEMBL1063754 0.78 KCNH2 (0.47) ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111019510-A Modified exposed single-component polyurethane waterproof coating and preparation method thereof 匡礼彬 2020-04-17 CN disclosed