Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373055 | 0.87 | ALDH1A1 (0.38) | OPRD1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL28373303 | 0.83 | ALOX5 (0.37) | OPRD1HNF4AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL28369314 | 0.82 | EPHX1 (0.43) | OPRD1HNF4AKDM4EMEN1KMT2A | |
| SCHEMBL28369893 | 0.71 | TSHR (0.43) | GAAL3MBTL1ALDH1A1TSHRMAPT | |
| SCHEMBL5008293 | 0.67 | GAA (0.56) | GAAL3MBTL1ALDH1A1TSHRMAPT | |
| SCHEMBL3042387 | 0.66 | MTNR1A (0.40) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL9821731 | 0.65 | MEN1 (0.37) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL8252070 | 0.65 | CA1 (0.52) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7473286 | 0.65 | MAPT (0.56) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6629846 | 0.65 | KCNH2 (0.50) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149602-B | Application of indole compounds and derivatives thereof in preparation of anti-HIV drugs | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |
| CN-107176921-B | Indole compounds with antiviral activity in isatis root and derivatives thereof | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |