SCHEMBL28375779

SCHEMBL28375779

CC(C)(C)C([SiH3])=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
AKR1C3 P42330 1/20 0.43
FBP1 P09467 3/20 0.39
AKR1C1 Q04828 1/20 0.38
ESR1 P03372 1/20 0.38
KDM1A O60341 1/20 0.37
RECQL P46063 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.36
EGFR P00533 1/20 0.36
NR1I2 O75469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765003 0.76 ALDH1A1 (0.46) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL4995920 0.76 ALDH1A1 (0.46) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL12593472 0.76 ALDH1A1 (0.46) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL8072809 0.75 ALDH1A1 (0.48) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL5549015 0.74 ALDH1A1 (0.50) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL11787435 0.74 ALDH1A1 (0.50) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL140742 0.73 ALDH1A1 (0.54) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL14633791 0.73 TSHR (0.44) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL241266 0.73 AKR1C1 (0.47) TSHRALDH1A1AKR1C3FBP1AKR1C1
SCHEMBL8857071 0.73 TSHR (0.43) TSHRALDH1A1AKR1C3FBP1AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884177-B Method for producing polymer 日产化学株式会社 2021-04-06 CN disclosed
CN-112375167-A Method for producing polymer 日产化学株式会社 2021-02-19 CN disclosed
CN-110997743-A Method for producing block polymer 日产化学株式会社 2020-04-10 CN disclosed
CN-110709430-A Method for producing block polymer 日产化学株式会社 2020-01-17 CN disclosed