Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 4/20 | 0.55 |
| ▸ | RXRB | P28702 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842987 | 0.90 | FOLH1 (0.49) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL9599418 | 0.85 | RXRA (0.46) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL2951399 | 0.82 | NR1H4 (0.51) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL30159253 | 0.82 | NR1H4 (0.51) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL27979983 | 0.82 | SRD5A2 (0.40) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL31628308 | 0.81 | ADH5 (0.56) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL16749637 | 0.81 | RXRA (0.66) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL11507830 | 0.81 | RARB (0.63) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL6566323 | 0.81 | RXRA (0.46) | ALDH1A1SMN1; SMN2RXRARXRBTP53 | |
| SCHEMBL16749653 | 0.80 | RXRA (0.59) | ALDH1A1SMN1; SMN2RXRARXRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111054443-A | Zirconium-based MOF catalyst loaded with double active sites and preparation method and application thereof | 华南理工大学 | 2020-04-24 | — | — | CN | claimed |
| CN-107774234-B | Metal organic framework material and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-107774234-B | Metal organic framework material and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-03-17 | — | — | CN | disclosed |