Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28376979 | 0.91 | SLC6A2 (0.38) | GPR35SLC6A2SLC6A4GRIN2DGRIN3B | |
| Diphenylether SCHEMBL28375871 | 0.89 | SLC6A2 (0.45) | GPR35SLC6A2SLC6A4SLC6A3PDK2 | |
| Benzophenone SCHEMBL28380275 | 0.84 | POLB (0.42) | GPR35SLC6A2SLC6A4PDK2ALDH1A1 | |
| SCHEMBL2795192 | 0.84 | SYK (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL6216607 | 0.84 | HRH1 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21945034 | 0.82 | GPR35 (0.40) | GPR35SLC6A2SLC6A4GRIN2DGRIN3B | |
| SCHEMBL2203963 | 0.81 | MET (0.45) | SLC6A2SLC6A4ALDH1A1MAPTTP53 | |
| SCHEMBL18002523 | 0.78 | GPR35 (0.38) | GPR35SLC6A2SLC6A4GRIN2DGRIN3B | |
| SCHEMBL16907535 | 0.78 | CHRNB2 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1263834 | 0.78 | SOS1 (0.46) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053474-B | Flexible diamine monomer, preparation method thereof and application thereof in preparation of polyimide | 吉林大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-109053470-B | Flexible diamine monomer, preparation method thereof and application thereof in preparation of polyimide | 吉林大学 | 2020-03-31 | — | — | CN | disclosed |