Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.44 |
| ▸ | KDM5A | P29375 | 5/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.44 |
| ▸ | KDM4A | O75164 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 3/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252466 | 0.84 | KMT2A (0.51) | KMT2AKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL27542831 | 0.80 | KDM4C (0.63) | KDM5BKDM5AKDM4CKDM4AKDM5C | |
| Hydrochloric Acid SCHEMBL30523486 | 0.79 | KDM4C (0.61) | KDM5BKDM5AKDM4CKDM4AKDM5C | |
| SCHEMBL16891458 | 0.78 | KLKB1 (0.49) | KMT2AKDM5BKDM4AHDAC1HDAC6 | |
| SCHEMBL5214363 | 0.77 | KDM5B (0.59) | KMT2AKDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL28105209 | 0.76 | KMT2A (0.60) | KMT2AHDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL16880902 | 0.75 | KLKB1 (0.47) | KMT2AKDM5BKDM5AKDM4CHDAC1 | |
| SCHEMBL5374862 | 0.75 | KMT2A (1.00) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL17442586 | 0.74 | KLKB1 (0.68) | KMT2AKLKB1MAP4K1 | |
| SCHEMBL16055756 | 0.74 | KDM4E (0.65) | KDM5BKDM5AKDM4CKDM4AKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |