SCHEMBL27542831

SCHEMBL27542831

O=C(O)c1ccnc(CCc2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 12/20 0.63
▸ KDM5B Q9UGL1 11/20 0.63
▸ KDM5A P29375 10/20 0.63
▸ KDM4A O75164 5/20 0.63
▸ KDM5C P41229 6/20 0.56
▸ KDM4E B2RXH2 4/20 0.56
▸ KDM6B O15054 3/20 0.51
▸ KDM2A Q9Y2K7 3/20 0.51
▸ KDM3A Q9Y4C1 3/20 0.51
▸ KDM2B Q8NHM5 2/20 0.50
▸ KDM4B O94953 1/20 0.50
▸ TET3 O43151 1/20 0.49
▸ BBOX1 O75936 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ ASPH Q12797 1/20 0.49
▸ KDM4D Q6B0I6 1/20 0.49
▸ TET2 Q6N021 1/20 0.49
▸ ALKBH5 Q6P6C2 1/20 0.49
▸ KDM7A Q6ZMT4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30523486 0.98 KDM4C (0.61) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL1568234 0.87 NR3C2 (0.51) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL27925527 0.85 KDM4C (0.62) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL4005621 0.84 KDM5B (0.51) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL28375307 0.81 KDM4C (0.54) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL28376364 0.80 KMT2A (0.57) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL9517033 0.80 KDM4C (0.52) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL481039 0.79 KDM4C (0.52) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL16055756 0.79 KDM4E (0.65) KDM4CKDM5BKDM5AKDM4AKDM5C
SCHEMBL1568230 0.78 KDM5B (0.46) KDM4CKDM5BKDM5AKDM4AKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1268942-A Sulfonamide compounds and medicinal use thereof FUJISAWA PHARMACEUTICAL CO (JP) 2000-10-04 — — CN disclosed
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