Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GALK1 | P51570 | 1/20 | 0.57 |
| ▸ | PLEC | Q15149 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381721 | 0.89 | LMNA (0.57) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL28382720 | 0.86 | KDM4E (0.41) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL28378055 | 0.84 | RAB9A (0.41) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL30594072 | 0.84 | RAB9A (0.41) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL30991482 | 0.79 | MAPT (0.78) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL15690641 | 0.79 | MAPT (0.78) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL28886770 | 0.78 | MAPT (0.61) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL28887599 | 0.75 | MEN1 (0.41) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL2556802 | 0.74 | MEN1 (0.70) | LMNAMAPTRAB9AL3MBTL1POLB | |
| SCHEMBL30594077 | 0.74 | RAB9A (0.41) | LMNAMAPTRAB9AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950749-A | IDO inhibitor and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-04-03 | — | — | CN | disclosed |