Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946004 | 0.74 | CHRM2 (0.33) | TDP1CHRM2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL708540 | 0.70 | MGLL (0.38) | MGLL | |
| SCHEMBL14063010 | 0.70 | MGLL (0.38) | MGLL | |
| SCHEMBL5495958 | 0.67 | TDP1 (0.45) | TDP1CHRM2ALDH1A1CYP3A4TSHR | |
| SCHEMBL822973 | 0.66 | ALDH1A1 (0.42) | TDP1ALDH1A1TP53SMN1; SMN2TSHR | |
| SCHEMBL18535692 | 0.65 | TDP1 (0.70) | TDP1ALDH1A1TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL1643921 | 0.65 | MEN1 (0.40) | TDP1CHRM2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3117376 | 0.65 | TDP1 (0.44) | TDP1CHRM2ALDH1A1TSHRDHFR | |
| SCHEMBL2720991 | 0.65 | TDP1 (0.70) | TDP1ALDH1A1TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL49248 | 0.65 | TDP1 (0.70) | TDP1ALDH1A1TP53SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110832003-A | Curable composition | 3M创新有限公司 | 2020-02-21 | — | — | CN | disclosed |