Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704776 | 0.90 | MEN1 (0.44) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL20704775 | 0.90 | MEN1 (0.44) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL20704873 | 0.82 | MEN1 (0.48) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL21931880 | 0.82 | MEN1 (0.48) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL13977272 | 0.76 | RAB9A (0.60) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL21992921 | 0.73 | RAB9A (0.50) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL21993197 | 0.70 | MEN1 (0.40) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL21993761 | 0.70 | MEN1 (0.82) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL21992963 | 0.67 | NME2 (0.42) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL31432758 | 0.66 | KMT2A (0.69) | MEN1KMT2AALDH1A1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032039-B | Compounds for the prevention and treatment of medical disorders and uses thereof | 卡莱克汀科学有限责任公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-111032039-A | Compounds for the prevention and treatment of medical disorders and uses thereof | 卡莱克汀科学有限责任公司 | 2020-04-17 | — | — | CN | disclosed |