SCHEMBL20704775

SCHEMBL20704775

COc1cc(/C=C2\CCn3c2nc(=O)c2c3CCN(C(=O)OC(C)(C)C)C2)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.44
▸ KMT2A Q03164 7/20 0.44
▸ MAPT P10636 5/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ POLB P06746 3/20 0.44
▸ KDM4E B2RXH2 3/20 0.44
▸ THRB P10828 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ RAB9A P51151 3/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ ALOX5 P09917 2/20 0.43
▸ JUN P05412 1/20 0.42
▸ MME P08473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20704776 1.00 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL28378783 0.90 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL21931880 0.79 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL20704873 0.79 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL13977272 0.73 RAB9A (0.60) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL21992921 0.71 RAB9A (0.50) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL20704871 0.70 ESR2 (0.42) MEN1KMT2AMAPTKDM4EMAPK1
SCHEMBL21993197 0.68 MEN1 (0.40) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL21993761 0.67 MEN1 (0.82) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL21993211 0.67 MEN1 (0.63) MEN1KMT2AMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC (US) 2026-03-05 — — US disclosed
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2025-08-05 — — US disclosed
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2023-04-13 — — US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
EP-3661502-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF MEDICAL DISORDERS AND USES THEREOF Galectin Sciences, LLC (US) 2020-06-10 — — EP disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed
WO-2019028357-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF MEDICAL DISORDERS AND USES THEREOF GALECTIN SCIENCES, LLC (US) 2019-02-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS3, LGALS1, LGALS2 MEN1 1652/4885KMT2A 4516/4885MAPT 2059/4885
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 MEN1 523/4885KMT2A 4754/4885MAPT 1108/4885
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 MEN1 523/4885KMT2A 4754/4885MAPT 1108/4885
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 MEN1 523/4885KMT2A 4754/4885MAPT 1108/4885
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 MEN1 523/4885KMT2A 4754/4885MAPT 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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