SCHEMBL28378944

SCHEMBL28378944

Brc1occ(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
MAPK1 P28482 2/20 0.43
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
PIN1 Q13526 2/20 0.35
BACE1 P56817 1/20 0.34
ALOX15 P16050 2/20 0.34
ALOX12 P18054 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 3/20 0.33
HPGD P15428 2/20 0.33
BCL2L1 Q07817 1/20 0.33
CTRC Q99895 1/20 0.33
TYMP P19971 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050786 0.82 CA2 (0.54) LMNACYP3A4
SCHEMBL6050734 0.82 PTGS2 (0.58)
SCHEMBL25706159 0.77 MAPT (0.39) ALDH1A1MAPK1MAPTLMNAHTT
SCHEMBL24818258 0.76 ALDH1A1 (0.40) ALDH1A1MAPTLMNAHTTPIN1
SCHEMBL5542767 0.74 BRD4 (0.44) ALDH1A1MAPTLMNAHTTPIN1
SCHEMBL7177675 0.74 MAPT (0.36) ALDH1A1MAPTLMNAHTTPIN1
SCHEMBL5542761 0.74 MAPT (0.36) ALDH1A1MAPTLMNAHTTPIN1
SCHEMBL28047614 0.74 CYP2A6 (0.43) ALDH1A1MAPTLMNAHTTPIN1
SCHEMBL11776755 0.72 MAPT (0.44) ALDH1A1MAPTLMNAHTTALOX15
SCHEMBL3977613 0.69 MAPT (0.37) ALDH1A1MAPTLMNAHTTPIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110845538-B Organic compound and application thereof 武汉天马微电子有限公司 2023-04-07 CN disclosed
CN-110845538-A Organic compound and application thereof 上海天马有机发光显示技术有限公司 2020-02-28 CN disclosed