Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632977 | 0.91 | SQOR (0.52) | KDM4ESQORALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27220350 | 0.86 | KDM4E (0.60) | KDM4ESQORALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27220349 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10MAPK1ADORA2A | |
| SCHEMBL7018629 | 0.86 | ADORA1 (0.54) | KDM4EALDH1A1HSD17B10MAPK1ADORA2A | |
| SCHEMBL6442682 | 0.86 | HSD17B10 (0.62) | KDM4ESQORALDH1A1HSD17B10MAPK1 | |
| SCHEMBL7016201 | 0.85 | ADORA1 (0.68) | KDM4EALDH1A1HSD17B10MAPK1ADORA2A | |
| SCHEMBL27220351 | 0.85 | KDM4E (0.53) | KDM4ESQORALDH1A1HSD17B10MAPK1 | |
| SCHEMBL28383673 | 0.84 | KDM4E (0.66) | KDM4ESQORALDH1A1HSD17B10ADORA2A | |
| SCHEMBL29666496 | 0.83 | ALDH1A1 (0.62) | KDM4ESQORALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1421425 | 0.82 | ADORA1 (0.56) | KDM4EALDH1A1HSD17B10ADORA2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018776-B | Synthesis method and application of pyridine derivative | 合肥工业大学 | 2023-05-26 | — | — | CN | claimed |
| CN-111018776-A | Synthesis method and application of pyridine derivative | 合肥工业大学 | 2020-04-17 | — | — | CN | claimed |
| CN-111018776-B | Synthesis method and application of pyridine derivative | 合肥工业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-111018776-A | Synthesis method and application of pyridine derivative | 合肥工业大学 | 2020-04-17 | — | — | CN | disclosed |