Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632977 | 0.87 | SQOR (0.52) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL27220349 | 0.85 | KDM4E (0.56) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL28379366 | 0.85 | KDM4E (0.58) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL6442682 | 0.80 | HSD17B10 (0.62) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL27220350 | 0.78 | KDM4E (0.60) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL13914338 | 0.77 | KDM4E (0.56) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL3554077 | 0.76 | ADORA1 (0.78) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL29442309 | 0.76 | SQOR (0.71) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL22215618 | 0.76 | SQOR (0.71) | KDM4ESMN1; SMN2RXFP1MAPK1ADORA1 | |
| SCHEMBL29666496 | 0.74 | ALDH1A1 (0.62) | KDM4EMAPK1ADORA1ADORA2APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986465-B1 | 2-amino-4-(4-bromophenyl)-6-ethoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11986465-B1 | 2-amino-4-(4-bromophenyl)-6-ethoxypyridine-3,5-dicarbonitrile as an antibacterial compound | CASP4, DCUN1D4, DCUN1D5 | KDM4E 519/4885SMN1; SMN2 3272/4885RXFP1 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.