SCHEMBL28380002

SCHEMBL28380002

COC1(OC)C=CC=CC1C(=O)C(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 10/20 0.39
CES1 P23141 9/20 0.39
TSHR P16473 3/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 4/20 0.33
KMT2A Q03164 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 2/20 0.32
ALOX15 P16050 1/20 0.32
NPC1 O15118 1/20 0.32
PAX8 Q06710 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10959754 0.85 NPC1 (0.40) CES2CES1TSHRMAPTKMT2A
SCHEMBL27926568 0.80 CES2 (0.41) CES2CES1RAB9AMAPTKMT2A
SCHEMBL27989123 0.77 CES2 (0.41) CES2CES1TSHRRAB9AMAPT
SCHEMBL28478305 0.77 CES2 (0.42) CES2CES1TSHRRAB9AMAPT
SCHEMBL17603239 0.73
SCHEMBL7132195 0.73 ALDH1A1 (0.38) TSHRRAB9AMAPTKMT2AHPGD
SCHEMBL867039 0.72
SCHEMBL2805922 0.72 NPC1 (0.40) CES2CES1TSHRMAPTKMT2A
SCHEMBL28442226 0.72 NPC1 (0.40) CES2CES1TSHRMAPTKMT2A
SCHEMBL7801403 0.71 TSHR (0.36) CES2CES1TSHRRAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059246-A Chemical bonding type rare earth light conversion film and preparation method and application thereof 中国科学院赣江创新研究院 2025-05-30 CN claimed
CN-116515159-B Preparation method of 3D printing organic nanofiber aerogel 东华大学 2025-05-30 CN claimed
CN-116515159-A Preparation method of 3D printing organic nanofiber aerogel 东华大学 2023-08-01 CN claimed
CN-113549167-B Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2022-12-09 CN claimed
CN-113549167-A Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2021-10-26 CN claimed
CN-116515159-B Preparation method of 3D printing organic nanofiber aerogel 东华大学 2025-05-30 CN disclosed
CN-120059246-A Chemical bonding type rare earth light conversion film and preparation method and application thereof 中国科学院赣江创新研究院 2025-05-30 CN disclosed
CN-118725264-A Fused heterocyclic polymer containing bisisoquinoline structure and preparation method and application thereof 深圳大学 2024-10-01 CN disclosed
CN-116515159-A Preparation method of 3D printing organic nanofiber aerogel 东华大学 2023-08-01 CN disclosed
CN-113549167-B Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2022-12-09 CN disclosed
CN-113549167-B Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2022-12-09 CN disclosed
CN-113549167-A Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2021-10-26 CN disclosed
CN-113549167-A Preparation process of efficient universal ultraviolet initiator 浙江东海新材料科技股份有限公司 2021-10-26 CN disclosed
CN-107419264-B Tire mold friction reducing plate and manufacturing process thereof 袁晓明 2020-04-17 CN disclosed