Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387493 | 0.92 | BTK (0.47) | MTORHDAC1LMNABTKMEN1 | |
| SCHEMBL28379449 | 0.90 | MTOR (0.54) | MTORHDAC1BTKMEN1KMT2A | |
| SCHEMBL28473090 | 0.90 | HDAC1 (0.62) | MTORHDAC1BTKMEN1KMT2A | |
| SCHEMBL28379450 | 0.89 | BTK (0.57) | BTK | |
| SCHEMBL28380138 | 0.88 | LMNA (0.51) | MTORHDAC1LMNAHTTBTK | |
| SCHEMBL30172728 | 0.87 | HDAC1 (0.51) | MTORHDAC1BTK | |
| SCHEMBL28382112 | 0.86 | ALDH1A1 (0.47) | MTORHDAC1POLBLMNABTK | |
| SCHEMBL28383968 | 0.85 | BTK (0.56) | MTORHDAC1BTKKDM4ETP53 | |
| SCHEMBL28384593 | 0.83 | FYN (0.47) | MTORHDAC1BTK | |
| SCHEMBL28383126 | 0.83 | HDAC1 (0.46) | MTORHDAC1P2RY14BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018865-A | 1-substituted benzyl pyrazolopyrimidine derivative and preparation method and application thereof | 山东大学 | 2020-04-17 | — | — | CN | claimed |