Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FHIT | P49789 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735138 | 0.75 | POLB (0.54) | LMNAALDH1A1CYP1A2POLBFHIT | |
| SCHEMBL16636292 | 0.74 | ALDH1A1 (0.46) | LMNAALDH1A1CYP1A2POLBFHIT | |
| SCHEMBL16797612 | 0.71 | LMNA (0.44) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL634161 | 0.69 | ESR2 (0.40) | LMNAALDH1A1CYP1A2POLBHPGD | |
| SCHEMBL999516 | 0.68 | ALDH1A1 (0.56) | ALDH1A1CYP1A2POLBHPGDMAPT | |
| SCHEMBL28979284 | 0.66 | GAA (0.52) | LMNAALDH1A1CYP1A2POLBFHIT | |
| SCHEMBL11588493 | 0.66 | MAPT (0.40) | LMNAALDH1A1CYP1A2POLBHPGD | |
| SCHEMBL908619 | 0.66 | ALDH1A1 (0.49) | LMNAALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL19028033 | 0.65 | TSHR (0.37) | LMNAALDH1A1POLBHPGDMAPT | |
| SCHEMBL16746890 | 0.65 | ALOX5 (0.46) | LMNAALDH1A1CYP1A2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116509-A | Method for recycling waste water from ethyl demethylaminothiazolyloximate production | 山东鑫泉医药有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-106699681-B | Synthetic method of ethyl noraminothiazolyloximate | 淄博鑫泉医药技术服务有限公司 | 2020-03-20 | — | — | CN | disclosed |