Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | KDM5C | P41229 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781584 | 0.81 | NPC1 (0.42) | NPC1RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL29072870 | 0.79 | KMT2A (0.43) | NPC1RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL28394531 | 0.79 | GABRP (0.58) | NPC1RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL28404952 | 0.79 | MAPT (0.44) | NPC1RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL3952413 | 0.79 | KDM4E (0.60) | NPC1RAB9AALDH1A1KDM4EALOX15 | |
| SCHEMBL19151580 | 0.76 | KDM5C (0.47) | ALDH1A1KDM4EMAPTKDM6BKDM5C | |
| SCHEMBL28883191 | 0.76 | MAPT (0.39) | NPC1RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL28422703 | 0.76 | ALDH1A1 (0.39) | NPC1RAB9AALDH1A1POLBKDM4E | |
| Nitrous Acid SCHEMBL28381983 | 0.75 | KDM4C (0.53) | ALDH1A1KDM4EMAPTKDM6BKDM5C | |
| SCHEMBL29117353 | 0.74 | PROKR1 (0.43) | NPC1RAB9AALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051305-A | Therapeutic heterocyclic compounds | 吉利德科学公司 | 2020-04-21 | — | — | CN | disclosed |