SCHEMBL28382016

SCHEMBL28382016

CCCCCC(=O)c1ccc(C)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.57
HSD17B3 P37058 7/20 0.50
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
HSD11B1 P28845 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 2/20 0.44
ALDH1A1 P00352 2/20 0.44
FFAR1 O14842 1/20 0.44
PLA2G2A P14555 1/20 0.44
PLA2G5 P39877 1/20 0.44
ATM Q13315 1/20 0.44
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14043029 0.95 HTT (0.50) HTTHSD17B3THRATHRBHSD11B1
SCHEMBL5569924 0.87 MEN1 (0.51) HTTHSD17B3THRATHRBHSD11B1
SCHEMBL4458634 0.86 THRA (0.45) HTTHSD17B3THRATHRBHSD11B1
SCHEMBL4451530 0.86 THRA (0.45) HTTHSD17B3THRATHRBHSD11B1
SCHEMBL10768782 0.85 MEN1 (0.63) HTTHSD17B3MEN1KMT2AGAA
SCHEMBL14032006 0.84 KMT2A (0.62) HTTHSD11B1MEN1KMT2AGAA
SCHEMBL11499565 0.84 SMN1; SMN2 (0.45) HTTTHRATHRBHSD11B1MEN1
SCHEMBL7390559 0.83 HSD11B1 (0.46) HTTHSD17B3THRATHRBHSD11B1
SCHEMBL8674913 0.83 HTT (0.71) HTTHSD17B3MEN1KMT2AGAA
SCHEMBL14540261 0.83 HTR7 (0.56) HTTHSD17B3THRATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-110950984-B Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN disclosed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-110950984-A Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2020-04-03 CN disclosed