SCHEMBL28382255

SCHEMBL28382255

CC(C)(C)[Si](C/C(=C/C(=O)O)C(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22558165 1.00 MAPT (0.37) MAPTKDM4ETSHRHTTCYP3A4
SCHEMBL4591664 0.78 CYP2C19 (0.42) MAPTCYP3A4CYP2C9RECQLCYP2C19
SCHEMBL13320021 0.75 MAPT (0.39) MAPTKDM4ECYP3A4CYP2C9CYP2C19
SCHEMBL7344627 0.73 MAPT (0.38) MAPTTSHRCYP3A4CYP2C9CYP2C19
SCHEMBL28423274 0.69 HTT (0.37) MAPTKDM4ETSHRHTTCYP2C19
SCHEMBL6675595 0.68 CYP2C19 (0.40) MAPTTSHRCYP3A4CYP2C19HIF1A
SCHEMBL8701181 0.68 CYP2C19 (0.38) MAPTTSHRCYP2C19HIF1A
SCHEMBL5839174 0.67 HCAR2 (0.50) MAPT
SCHEMBL5838532 0.67 HCAR2 (0.50) MAPT
SCHEMBL5838529 0.67 HCAR2 (0.50) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111065685-B Macromonomer copolymer, epoxy resin composition, adhesive, molding material, and cured product 三菱化学株式会社 2022-12-23 CN disclosed
CN-107207819-B Antifouling coating composition 三菱化学株式会社 2021-06-22 CN disclosed
CN-112771090-A Copolymer for inhibiting protein adhesion, method for producing copolymer, resin modifier, molding material, composition containing copolymer, coating film, and article 三菱化学株式会社 2021-05-07 CN disclosed
CN-111065685-A Macromonomer copolymer, epoxy resin composition, adhesive, molding material, and cured product 三菱化学株式会社 2020-04-24 CN disclosed