Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320021 | 0.87 | MAPT (0.39) | MAPTCYP2C19HIF1ANPC1RAB9A | |
| SCHEMBL4591664 | 0.83 | CYP2C19 (0.42) | MAPTCYP2C19HIF1ANPC1RAB9A | |
| SCHEMBL8701181 | 0.77 | CYP2C19 (0.38) | MAPTCYP2C19HIF1ATSHRCES2 | |
| SCHEMBL22558165 | 0.73 | MAPT (0.37) | MAPTCYP2C19HIF1ATSHRCYP2C9 | |
| SCHEMBL28382255 | 0.73 | MAPT (0.37) | MAPTCYP2C19HIF1ATSHRCYP2C9 | |
| SCHEMBL506540 | 0.73 | NR1H2 (0.33) | MAPTCYP2C19HIF1ATSHRNPC1 | |
| SCHEMBL6675595 | 0.73 | CYP2C19 (0.40) | MAPTCYP2C19HIF1ATSHRNPC1 | |
| SCHEMBL8350263 | 0.71 | SMYD2 (0.34) | MAPTCYP2C19HIF1ATSHRNPC1 | |
| SCHEMBL8878189 | 0.70 | HDAC3 (0.43) | MAPTCYP2C19HIF1ATSHRSMN1; SMN2 | |
| SCHEMBL21834438 | 0.70 | SLC13A5 (0.43) | MAPTCYP2C19HIF1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031476-A1 | AROMATIC HYDROXYETHERS | RHONE-POULENC RORER LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |