Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283971 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL283828 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL283972 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL18502884 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL14922428 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL49036 | 0.90 | — | — | |
| SCHEMBL21452521 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL14098332 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL21238474 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EATMCA1CA2 | |
| SCHEMBL18474342 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EATMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077120-A1 | PHOTORESISTS COMPRISING MULTI-AMIDE COMPONENT | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2012-03-29 | — | — | US | claimed |
| EP-2428842-A1 | Photoresists comprising multi-amide component | Rohm and Haas Electronic Materials LLC (US) | 2012-03-14 | — | — | EP | claimed |
| US-9779901-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2017-10-03 | — | — | US | disclosed |
| US-20150162153-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2015-06-11 | — | — | US | disclosed |
| US-8961832-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2015-02-24 | — | — | US | disclosed |
| EP-2151846-B1 | High temperature thermal cutoff device | THERM O DISC INC (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120077120-A1 | PHOTORESISTS COMPRISING MULTI-AMIDE COMPONENT | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2012-03-29 | — | — | US | disclosed |
| EP-2428842-A1 | Photoresists comprising multi-amide component | Rohm and Haas Electronic Materials LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| CN-101685733-A | High-temperature thermal fuse device | THERM O DISC INC | 2010-03-31 | — | — | CN | disclosed |
| US-20100033295-A1 | HIGH TEMPERATURE THERMAL CUTOFF DEVICE | THERM-O-DISC, INCORPORATED (US) | 2010-02-11 | — | — | US | disclosed |
| EP-2151846-A2 | High temperature thermal cutoff device | Therm-O-Disc Incorporated (US) | 2010-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | HTT, HTR1A, TPH1 | ALDH1A1 410/4885KDM4E 2059/4885ATM 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.