Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345805 | 0.94 | TSHR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL21483689 | 0.85 | KMT2A (0.43) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11698031 | 0.85 | LMNA (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL131571 | 0.85 | LMNA (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL5711602 | 0.83 | PLA2G4B (0.48) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL25419167 | 0.83 | PGR (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL9223639 | 0.82 | PGR (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL16221406 | 0.82 | KMT2A (0.55) | LMNAL3MBTL1PLA2G4BMEN1KMT2A | |
| SCHEMBL9005002 | 0.82 | LMNA (0.45) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL29549835 | 0.82 | LMNA (0.45) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417643-B | Synthesis process of dyclonine hydrochloride | 贵州神奇药业有限公司 | 2020-05-01 | — | — | CN | disclosed |