Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559563 | 0.98 | LMNA (0.33) | LMNAKDM4EADORA3PKMADORA2A | |
| Hydrochloric Acid SCHEMBL20473874 | 0.96 | LMNA (0.33) | LMNAKDM4EADORA3PKMADORA2A | |
| SCHEMBL24708463 | 0.79 | LMNA (0.33) | LMNAKDM4EADORA3PKMADORA2A | |
| SCHEMBL12126347 | 0.78 | IKBKB (0.34) | — | |
| SCHEMBL5287479 | 0.77 | POLB (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL11562510 | 0.77 | L3MBTL1 (0.33) | LMNAKDM4EADORA3PKMADORA2A | |
| SCHEMBL17000560 | 0.76 | L3MBTL1 (0.30) | LMNAKDM4E | |
| SCHEMBL22083545 | 0.75 | POLB (0.35) | LMNAKDM4EPKM | |
| SCHEMBL20988688 | 0.75 | ALDH1A1 (0.31) | LMNAKDM4EADORA3PKMADORA2A | |
| SCHEMBL12126191 | 0.73 | TSHR (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315733-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111093773-A | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | 英夫拉索姆有限公司 | 2020-05-01 | — | — | CN | disclosed |