Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326216 | 0.78 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL20266316 | 0.78 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL15032485 | 0.75 | MAPT (0.60) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL17582666 | 0.75 | MAPT (0.50) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL11673614 | 0.74 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL13526111 | 0.71 | ACHE (0.36) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL30274237 | 0.71 | GAA (0.38) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| Bicarbonate SCHEMBL29098908 | 0.70 | GAA (0.38) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11086067 | 0.68 | MAPT (0.55) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL18561732 | 0.68 | NQO2 (0.36) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |