Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068239 | 0.80 | TDP1 (0.36) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL3691516 | 0.79 | ALDH1A1 (0.35) | MEN1LMNATHRBKMT2AALDH1A1 | |
| SCHEMBL7344090 | 0.74 | ALDH1A1 (0.35) | ALDH1A1CYP2A6KDM4EPTGS2RAB9A | |
| SCHEMBL14222970 | 0.74 | ERN1 (0.45) | KDM4EERN1PTGS2RAB9A | |
| SCHEMBL1488401 | 0.72 | ERN1 (0.61) | KDM4EERN1PTGS2RAB9AALDH5A1 | |
| SCHEMBL6516051 | 0.72 | TDP1 (0.35) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL548045 | 0.72 | ERN1 (0.42) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL28385480 | 0.72 | ALDH1A1 (0.43) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL308093 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP2A6KDM4EPTGS2RAB9A | |
| SCHEMBL178489 | 0.71 | CYP19A1 (0.46) | ALDH1A1CYP2A6KDM4EPTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |