Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 9/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901379 | 0.87 | MEN1 (0.32) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL28387342 | 0.80 | TDP1 (0.35) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL9218249 | 0.74 | LMNA (0.31) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL14877337 | 0.72 | ALDH1A1 (0.38) | TDP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27819554 | 0.72 | ERN1 (0.46) | LMNATHRBMAPTERN1 | |
| SCHEMBL27915781 | 0.72 | ERN1 (0.47) | ERN1 | |
| SCHEMBL11664879 | 0.72 | LMNA (0.46) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL29139204 | 0.71 | KMT2A (0.58) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL135290 | 0.70 | TDP1 (0.40) | TDP1LMNAMEN1THRBBLM | |
| SCHEMBL8693955 | 0.70 | ALDH1A1 (0.41) | TDP1LMNAMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105694029-A | Poly(isophthaloyl p-phenylenediamine) and interfacial polycondensation based preparation method thereof | 南华大学 | 2016-06-22 | — | — | CN | disclosed |