SCHEMBL28387481

SCHEMBL28387481

CCCCCCCCCc1ccc(C(=O)Oc2ccc(-c3cc(OCCCCCCOC4CCCCO4)ccc3C(=O)O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PTPN11 Q06124 4/20 0.47
RARB P10826 11/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 1/20 0.41
PTPRC P08575 1/20 0.39
PTPRF P10586 1/20 0.39
PTPN1 P18031 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
CDC25C P30307 1/20 0.39
PPP1CC P36873 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
RARA P10276 1/20 0.39
RARG P13631 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431457 0.88 KMT2A (0.62) MEN1KMT2ASMN1; SMN2MAPTNFKB1
SCHEMBL11219166 0.80 BRS3 (0.43) MEN1KMT2APTPN11RARBSMN1; SMN2
SCHEMBL9193021 0.79 PTPN11 (0.66) MEN1KMT2APTPN11RARBMAPT
SCHEMBL8044985 0.79 PTPN11 (0.66) MEN1KMT2APTPN11RARBMAPT
SCHEMBL9619553 0.79 PTPN11 (0.66) MEN1KMT2APTPN11RARBMAPT
SCHEMBL7981006 0.79 PTPN11 (0.66) MEN1KMT2APTPN11RARBMAPT
SCHEMBL2433889 0.79 PTPN11 (0.54) PTPN11RARBSMN1; SMN2MAPTNFKB1
SCHEMBL1925578 0.79 PTPN11 (0.54) PTPN11RARBSMN1; SMN2MAPTNFKB1
SCHEMBL1531771 0.79 MEN1 (0.73) MEN1KMT2ARARBSMN1; SMN2NFKB1
SCHEMBL28696354 0.79 KMT2A (0.52) MEN1KMT2APTPN11SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111033777-B Dielectric layer comprising copolymer with mesogenic units PPG工业俄亥俄公司 2023-08-08 CN disclosed
CN-111033777-A Dielectric layer comprising copolymer with mesogenic units PPG工业俄亥俄公司 2020-04-17 CN disclosed