Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM6A | O15550 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.35 |
| ▸ | CBFB | Q13951 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297698 | 0.85 | KDM6B (0.47) | ESR1KDM6BKDM6AALDH1A1GAA | |
| SCHEMBL29188907 | 0.73 | NPC1 (0.35) | ESR1KDM6BKDM6AALDH1A1GAA | |
| SCHEMBL2800972 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDHTTNPC1 | |
| SCHEMBL9364714 | 0.68 | ACHE (0.47) | ESR1MAPTNPC1GUSBSNCA | |
| SCHEMBL9144585 | 0.67 | SNCA (0.75) | ESR1MAPTGUSBSNCAESR2 | |
| SCHEMBL2112019 | 0.66 | NPC1 (0.58) | ALDH1A1GAAMAPTHPGDNPC1 | |
| SCHEMBL11520804 | 0.64 | NPC1 (0.44) | ALDH1A1MAPTHPGDHTTGFER | |
| SCHEMBL259088 | 0.63 | ALDH1A1 (0.54) | ESR1KDM6BKDM6AALDH1A1GAA | |
| SCHEMBL29484153 | 0.63 | ALDH1A1 (0.54) | ESR1KDM6BKDM6AALDH1A1GAA | |
| SCHEMBL14093883 | 0.63 | SNCA (0.47) | ALDH1A1MAPTHPGDNPC1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056914-A1 | BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF | MICROBIOTIX, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| WO-2010056914-A1 | BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF | MICROBIOTIX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010056914-A1 | BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF | MICROBIOTIX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |