Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.83 |
| ▸ | CA1 | P00915 | 6/20 | 0.83 |
| ▸ | CA9 | Q16790 | 4/20 | 0.83 |
| ▸ | CA5A | P35218 | 1/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonamide SCHEMBL1546211 | 0.91 | CA2 (0.91) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL7371 | 0.91 | CA2 (1.00) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL4428481 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL3638470 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL9400757 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL9006012 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL4059166 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL31442719 | 0.89 | CA2 (0.95) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL9492234 | 0.84 | CA2 (0.86) | CA2CA1CA9CA5APRSS1 | |
| Phenylmethanesulfonamide SCHEMBL5045100 | 0.81 | CA2 (0.79) | CA2CA1CA9CA5APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452143-B | Method for mildly and efficiently synthesizing 1, 3-disulfide derivative | 西南民族大学 | 2020-04-28 | — | — | CN | disclosed |