Phenylmethanesulfonamide

Phenylmethanesulfonamide

SCHEMBL7371

NS(=O)(=O)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 1.00
CA1 P00915 7/20 1.00
CA9 Q16790 5/20 1.00
CA5A P35218 2/20 1.00
PRSS1 P07477 2/20 0.58
PRSS2 P07478 2/20 0.58
PRSS3 P35030 2/20 0.58
FAAH O00519 1/20 0.58
ELANE P08246 1/20 0.58
PRTN3 P24158 1/20 0.58
CA12 O43570 3/20 0.52
CA14 Q9ULX7 3/20 0.52
CA7 P43166 2/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
F2 P00734 1/20 0.52
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylmethanesulfonamide SCHEMBL9400757 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL9006012 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL4428481 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL31442719 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL3638470 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL4059166 0.97 CA2 (0.95) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL1546211 0.95 CA2 (0.91) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL9492234 0.93 CA2 (0.86) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL28388564 0.91 CA2 (0.83) CA2CA1CA9CA5APRSS1
Phenylmethanesulfonamide SCHEMBL5045100 0.89 CA2 (0.79) CA2CA1CA9CA5APRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13181 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745119-A1 ISOCYANATE COMPOSITION Hanwha Solutions Corporation (KR) 2026-05-20 EP claimed
EP-4741826-A1 ANTI-NEPHRIN AUTOANTIBODY ASSAY KIT, DETECTION METHOD THEREFOR AND PREPARATION METHOD THEREFOR Shenzhen Yhlo Biotech Co., Ltd. (CN) 2026-05-13 EP claimed
EP-4720206-A1 INVISIBLE FLUORESCENT SOLVENT INK JET INK COMPOSITIONS Videojet Technologies, Inc. (US) 2026-04-08 EP claimed
US-20260062581-A1 INVISIBLE FLUORESCENT SOLVENT INK JET INK COMPOSITIONS VIDEOJET TECHNOLOGIES INC. (US) 2026-03-05 US claimed
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
EP-4628558-A1 POLYETHYLENE TEREPHTHALATE-BASED ADHESIVE REPAIR PATCH FOR ANTI-CORROSIVE COATINGS, METHOD FOR PRODUCING SAME AND USE THEREOF Petroleo Brasileiro S.A. - PETROBRAS (BR) 2025-10-08 EP claimed
US-12385918-B2 IgA antibodies and kits capable of specifically recognizing RBD protein SHENZHEN YHLO BIOTECH CO., LTD (CN) 2025-08-12 US claimed
EP-4032923-B1 THERMOSETTING RESIN COMPOSITION FOR LAMINATE PANEL, METHOD FOR MANUFACTURING A PANEL WITH A THERMOSETTING RESIN COMPOSITION AND A LAMINATE PANEL COMPRISING A THERMOSETTING RESIN UNILIN BV (BE) 2025-08-06 EP claimed
CN-119977850-A Urea derivative containing aryl sulfonamide structure, and preparation method and application thereof 沈阳药科大学 2025-05-13 CN claimed
CN-119751229-A Synthesis method of phenylephrine intermediate 3-hydroxy-2' -chloroacetophenone derivative 深圳格林凯特医药技术有限公司 2025-04-04 CN claimed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US claimed
US-4240832-A CALCIUM HYDROXIDE WITH CONDENSATE OF A SALICYLATE ESTER AND AN ALDEHYDE SYBRON CORPORATION (US) 1980-12-23 US claimed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
US-4217406-A Cross-linking reaction during melt kneading produces resinous electrophotographic toner FUJI XEROX CO. LTD. (JP) 1980-08-12 US claimed
US-4133843-A ETHERIFIED AROMATIC SULFONAMIDE AMINOPLAST, POLYESTER OR ACRYLIC RESIN MONSANTO COMPANY (US) 1979-01-09 US claimed
US-4001628-A LOW-PRESSURE FLUORESCENT DISCHARGE DEVICE WHICH UTILIZES BOTH INORGANIC AND ORGANIC PHOSPHORS WESTINGHOUSE ELECTRIC CORPORATION (US) 1977-01-04 US claimed
US-3994972-A Synthesis of N,N',N\",N'\"-tetra-salicylidene pentaerythrityl tetramine HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-11-30 US claimed
US-3980733-A CONDENSATE OF A METHYLOL-UREA OR METHYLOL AMINO TRIAZINE WITH AN ALIPHATIC- ALCOHOL OR AMINE MONSANTO COMPANY (US) 1976-09-14 US claimed
US-3960744-A BLUING DYE PRECURSOR, BUILDER KAO SOAP CO., LTD. (JA) 1976-06-01 US claimed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US claimed