Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.57 |
| ▸ | TUBB | P07437 | 4/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307941 | 0.80 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL857391 | 0.75 | AXL (0.45) | KMT2AGPR84 | |
| SCHEMBL4068600 | 0.73 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9328490 | 0.72 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL34463637 | 0.72 | TUBB4A (0.96) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL858164 | 0.69 | NR4A2 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31397682 | 0.69 | RHEB (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13236404 | 0.69 | GFER (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31397683 | 0.69 | GFER (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31397676 | 0.69 | GFER (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | disclosed |