Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 1.00 |
| ▸ | TUBB | P07437 | 2/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 2/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 2/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 2/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 2/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 2/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 1.00 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 1.00 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 1.00 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 1.00 |
| ▸ | IDO1 | P14902 | 5/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34463637 | 0.98 | TUBB4A (0.96) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25356196 | 0.89 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5307941 | 0.87 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28515820 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22802294 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29629604 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5776244 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22802286 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7498794 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29988391 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | claimed |
| US-20200399217-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RESEARCH CORPORATION | 2020-12-24 | — | — | US | claimed |
| US-20200399218-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RESEARCH CORPORATION | 2020-12-24 | — | — | US | claimed |
| CN-111100056-A | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2020-05-05 | — | — | CN | claimed |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| US-12202798-B2 | Antimicrobial compounds, compositions, and articles of manufacture for selectively inhibiting pathogenic microbes | CFD RESEARCH CORPORATION (US) | 2025-01-21 | — | — | US | disclosed |
| US-11180452-B2 | Methods and compositions for selectively inhibiting pathogenic microbes | CFD RESEARCH CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-11180452-B2 | Methods and compositions for selectively inhibiting pathogenic microbes | CFD RESEARCH CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| CN-111100056-B | Synthetic method for preparing 3-thiophenyl indole compound by oxygen oxidation without transition metal catalysis | 浙江工业大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-108586312-B | Green sulfuration method of indole compound by using triphosgene as reducing agent | 丽水学院 | 2021-03-05 | — | — | CN | disclosed |
| US-20200399218-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RESEARCH CORPORATION | 2020-12-24 | — | — | US | disclosed |
| US-20030232828-A1 | 1-(AMINOALKYL)-3-SULFONYLINDOLE AND-INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH | 2003-12-18 | — | — | US | disclosed |
| US-20030130337-A1 | Indole derivatives as anti-inflammatory agents | SYNTEX (U.S.A.) LLC | 2003-07-10 | — | — | US | disclosed |
| EP-0924209-B1 | Hypoglycemic imidazoline compounds | LILLY CO ELI (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003029212-A1 | INDOLE DERIVATIVES AS COX II INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |
| EP-1266897-A2 | Hypoglycemic imidazoline compounds | ELI LILLY AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6410562-B1 | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY | 2002-06-25 | — | — | US | disclosed |
| EP-0924209-A1 | Hypoglycemic imidazoline compounds | ELI LILLY AND COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| US-4654360-A | 1,2,3-trisubstituted indoles for treatment of inflammation | SYNTEX (U.S.A.) INC. (US) | 1987-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130337-A1 | Indole derivatives as anti-inflammatory agents | IDO1, IDO2, PTGS1 | TUBB4A 2545/4885TUBB 2149/4885TUBA3C 2203/4885 |
| US-12202798-B2 | Antimicrobial compounds, compositions, and articles of manufacture for selectively inhibiting pathogenic microbes | ZYX, IDO1, CRY1 | TUBB4A 2312/4885TUBB 2695/4885TUBA3C 2269/4885 |
| US-11180452-B2 | Methods and compositions for selectively inhibiting pathogenic microbes | FPR1, FPR3, ARG1 | TUBB4A 2901/4885TUBB 2885/4885TUBA3C 2645/4885 |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | TUBB4A 2340/4885TUBB 1711/4885TUBA3C 2384/4885 |
| US-20200399217-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | FPR1, FPR3, ARG1 | TUBB4A 2901/4885TUBB 2885/4885TUBA3C 2645/4885 |
| US-20030232828-A1 | 1-(AMINOALKYL)-3-SULFONYLINDOLE AND-INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | HTR6, HTR3A, HTR5A | TUBB4A 1421/4885TUBB 813/4885TUBA3C 661/4885 |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | TUBB4A 2340/4885TUBB 1711/4885TUBA3C 2384/4885 |
| US-20200399218-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | ZYX, IDO1, CRY1 | TUBB4A 2312/4885TUBB 2695/4885TUBA3C 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.