Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381467 | 0.92 | MEN1 (0.88) | SMN1; SMN2KMT2AMEN1MAPTRECQL | |
| SCHEMBL28393986 | 0.91 | MAPT (0.93) | SMN1; SMN2KMT2AMEN1MAPTRECQL | |
| SCHEMBL28389907 | 0.91 | MAPT (0.93) | SMN1; SMN2KMT2AMEN1MAPTRECQL | |
| SCHEMBL2988108 | 0.89 | MEN1 (0.82) | SMN1; SMN2KMT2AMEN1MAPTRECQL | |
| SCHEMBL2988105 | 0.89 | MEN1 (0.82) | SMN1; SMN2KMT2AMEN1MAPTRECQL | |
| SCHEMBL12443153 | 0.86 | MEN1 (1.00) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL12443128 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| N'-(4-Methylbenzylidene)Isonicotinohydrazide SCHEMBL12443123 | 0.85 | L3MBTL1 (1.00) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL12443125 | 0.85 | NPC1 (0.77) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| N'-Benzylidene Isonicotinohydrazide SCHEMBL28282742 | 0.84 | KMT2A (0.75) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178077-A1 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | SMN1; SMN2 4839/4885KMT2A 4781/4885MEN1 3685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.