Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylphenylsulfone SCHEMBL13268482 | 0.84 | PTGS2 (0.43) | ALDH1A1PTGS2AKR1C2AKR1C1AKR1C3 | |
| Bromobenzene SCHEMBL28390266 | 0.80 | ELANE (0.39) | ALDH1A1ELANE | |
| Methylphenylsulfone SCHEMBL28390314 | 0.79 | ALDH1A1 (0.38) | ALDH1A1PTGS2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL28386391 | 0.77 | ELANE (0.31) | ELANE | |
| SCHEMBL28398450 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GAAHSD17B10 | |
| Methylphenylsulfone SCHEMBL13268396 | 0.73 | HPGD (0.44) | ALDH1A1GAAHSD17B10 | |
| Methylphenylsulfone SCHEMBL28389024 | 0.73 | ALDH1A1 (0.41) | ALDH1A1GAA | |
| Methylphenylsulfone SCHEMBL17498119 | 0.72 | KDM4E (0.50) | ALDH1A1PTGS2HSD17B10 | |
| Methylphenylsulfone SCHEMBL28888116 | 0.71 | MAPK1 (0.41) | ALDH1A1PTGS2GAAHSD17B10 | |
| Methylphenylsulfone SCHEMBL17498177 | 0.71 | KAT2B (0.40) | PTGS2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105919987-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives and uses thereof | 约翰斯霍普金斯大学 | 2020-04-03 | — | — | CN | disclosed |