Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL29024223 | 1.00 | TSHR (0.39) | TSHRALDH1A1CA5ACA5BLMNA | |
| SCHEMBL1904 | 0.88 | — | — | |
| SCHEMBL126970 | 0.88 | — | — | |
| SCHEMBL2058760 | 0.88 | CA5A (0.46) | TSHRALDH1A1CA5ACA5BLMNA | |
| Ethylene Glycol SCHEMBL2166131 | 0.87 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL2167465 | 0.87 | FFAR3 (0.41) | ALDH1A1SMN1; SMN2TDP1 | |
| 1,4-Butanediol SCHEMBL575604 | 0.86 | SMN1; SMN2 (0.50) | TSHRALDH1A1LMNAPTGS1PDE4A | |
| 1,3-Propanediol SCHEMBL575455 | 0.86 | ALDH1A1 (0.44) | TSHRALDH1A1CA5ACA5BLMNA | |
| Alcohol SCHEMBL27753103 | 0.85 | TSHR (0.46) | TSHRALDH1A1CA5ACA5BLMNA | |
| Sulfuric Acid SCHEMBL443702 | 0.85 | CA5A (0.46) | TSHRALDH1A1CA5ACA5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111154098-B | Polyelectrolyte, preparation method and application thereof | 湘潭大学 | 2022-07-05 | — | — | CN | claimed |
| CN-111154098-A | Polyelectrolyte, preparation method and application thereof | 湘潭大学 | 2020-05-15 | — | — | CN | claimed |
| CN-115911573-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-111154098-B | Polyelectrolyte, preparation method and application thereof | 湘潭大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-106848406-B | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2020-09-11 | — | — | CN | disclosed |
| CN-111154098-A | Polyelectrolyte, preparation method and application thereof | 湘潭大学 | 2020-05-15 | — | — | CN | disclosed |
| CN-111048841-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2020-04-21 | — | — | CN | disclosed |
| CN-105633345-B | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2020-01-17 | — | — | CN | disclosed |