Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of 1,4-Butanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL575455 | 0.93 | ALDH1A1 (0.44) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| 1,4-Butanediol SCHEMBL2167602 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| 1,4-Butanediol SCHEMBL2168624 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Tridecan-1-Ol SCHEMBL28721719 | 0.87 | LMNA (0.65) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Ethylene Glycol SCHEMBL28390899 | 0.86 | TSHR (0.39) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| Ethylene Glycol SCHEMBL29024223 | 0.86 | TSHR (0.39) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| 1,4-Butanediol SCHEMBL575703 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL11145288 | 0.83 | APP (0.52) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| 1,4-Butanediol SCHEMBL20236034 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 | |
| 1,4-Butanediol SCHEMBL15301979 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240297344-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| US-11616253-B2 | Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-03-28 | — | — | US | disclosed |
| US-20220278370-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-09-01 | — | — | US | disclosed |
| US-11367899-B2 | Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-06-21 | — | — | US | disclosed |
| US-11114693-B2 | Electrolytic solution for nonaqueous electrolytic solution secondary batteries and nonaqueous electrolytic solution secondary battery | CENTRAL GLASS COMPANY, LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3333962-B1 | ELECTROLYTIC SOLUTION FOR NONAQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERIES AND NONAQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY | CENTRAL GLASS CO LTD (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-20200212485-A1 | Non-Aqueous Electrolyte Solution and Non-Aqueous Electrolyte Battery in Which Same Is Used | CENTRAL GLASS COMPANY, LIMITED (JP) | 2020-07-02 | — | — | US | disclosed |
| US-10468720-B2 | Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190288338-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-09-19 | — | — | US | disclosed |
| EP-2144321-B1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEM CORP (JP) | 2019-01-23 | — | — | EP | disclosed |
| EP-2360771-A1 | Nonaqueous electrolytic solutions and nonaqueous-electrolyte batteries | Mitsubishi Chemical Corporation (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20100255384-A1 | Nonaqueous electrolyte secondary battery | PANASONIC ENERGY CO., LTD (JP) | 2010-10-07 | — | — | US | disclosed |
| US-7767343-B2 | Nonaqueous electrolyte secondary battery using lithium cobalt oxide as a positive active material and a nonaqueous electrolyte containing a sulfonyl-containing compound | UBE INDUSTRIES LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20100119956-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2144321-A1 | NONAQUEOUS ELECTROLYTE FOR RECHARGEABLE BATTERY, AND RECHARGEABLE BATTERY WITH NONAQUEOUS ELECTROLYTE | Mitsubishi Chemical Corporation (JP) | 2010-01-13 | — | — | EP | disclosed |
| US-20090253045-A1 | NONAQUEOUS ELECTROLYTIC SOLUTIONS AND NONAQUEOUS-ELECTROLYTE BATTERIES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-2031689-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY | Mitsubishi Chemical Corporation (JP) | 2009-03-04 | — | — | EP | disclosed |
| EP-1739783-A1 | NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | Ube Industries, Ltd. (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-20060166096-A1 | Nonaqueous electrolyte secondary battery | PANASONIC ENERGY CO., LTD (JP) | 2006-07-27 | — | — | US | disclosed |
| US-6436582-B1 | A NON-AQUEOUS SOLVENT AND (II) AN ELECTROLYTE SALT DISSOLVED THEREIN AND (III) A DISULFONATE ESTER DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11114693-B2 | Electrolytic solution for nonaqueous electrolytic solution secondary batteries and nonaqueous electrolytic solution secondary battery | ESPL1, TST, PEF1 | SMN1; SMN2 869/4885LMNA 2885/4885ALDH1A1 1379/4885 |
| US-20200212485-A1 | Non-Aqueous Electrolyte Solution and Non-Aqueous Electrolyte Battery in Which Same Is Used | SLC9A1, TST, CA1 | SMN1; SMN2 735/4885LMNA 3281/4885ALDH1A1 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.