Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956090 | 0.79 | MAOB (0.59) | GAAALDH1A1MAOBPSMB5KMT2A | |
| SCHEMBL28390935 | 0.76 | GAA (0.71) | LMNAGAAALDH1A1MAOBL3MBTL1 | |
| SCHEMBL28902178 | 0.71 | MAOB (0.60) | LMNAALDH1A1KDM4CMAOBL3MBTL1 | |
| SCHEMBL30956075 | 0.71 | MAOB (0.52) | LMNAGAAALDH1A1KDM4CMAOB | |
| SCHEMBL28902182 | 0.71 | MAOB (0.74) | GAAALDH1A1MAOBPSMB5KMT2A | |
| SCHEMBL31744579 | 0.70 | PSMB5 (0.49) | ALDH1A1KDM4CMAOBPSMB5MAPT | |
| SCHEMBL20208682 | 0.70 | CYP1A2 (0.54) | — | |
| SCHEMBL3319344 | 0.70 | GAA (0.47) | LMNAGAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL3114555 | 0.70 | EGFR (0.47) | LMNAGAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30956067 | 0.70 | KDM4C (0.51) | KDM4CMAOBPSMB5CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |