Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13605865 | 0.83 | NAMPT (0.57) | NAMPTSLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL21960093 | 0.83 | ALDH1A1 (0.54) | NAMPTSLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL8285763 | 0.81 | MAPT (0.49) | NAMPTSLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL28888409 | 0.79 | SLC1A3 (0.50) | NAMPTSLC1A3SLC1A2SLC1A1CYP4F2 | |
| SCHEMBL6281607 | 0.77 | NAMPT (0.59) | NAMPTMAPTALDH1A1SLC2A1SMN1; SMN2 | |
| SCHEMBL21968424 | 0.76 | PTGS2 (0.51) | NAMPTSLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL3447394 | 0.75 | ALDH1A1 (0.59) | NAMPTSLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL12880366 | 0.75 | PTGS2 (0.52) | SLC1A3SLC1A2SLC1A1CYP2C19NAPRT | |
| SCHEMBL13227934 | 0.75 | MAPT (0.49) | NAMPTSLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL21960091 | 0.74 | NAPRT (0.57) | SLC1A3SLC1A2SLC1A1CYP2C19NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105919987-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives and uses thereof | 约翰斯霍普金斯大学 | 2020-04-03 | — | — | CN | disclosed |