Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21960087 | 0.82 | NAPRT (0.52) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL30530541 | 0.82 | MAPT (0.54) | SLC1A3SLC1A2SLC1A1NAPRTKEAP1 | |
| SCHEMBL858995 | 0.82 | MAPT (0.54) | SLC1A3SLC1A2SLC1A1NAPRTKEAP1 | |
| SCHEMBL10402270 | 0.82 | BCAT1 (0.50) | KEAP1ALDH1A1PLGPLAUPLAT | |
| SCHEMBL28391735 | 0.79 | NAMPT (0.49) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL579072 | 0.77 | KMT2A (0.50) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL12880366 | 0.77 | PTGS2 (0.52) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL1464706 | 0.76 | NAPRT (0.53) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL25394823 | 0.76 | PTGS2 (0.62) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 | |
| SCHEMBL486015 | 0.76 | KMT2A (0.55) | SLC1A3SLC1A2SLC1A1NAPRTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105919987-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives and uses thereof | 约翰斯霍普金斯大学 | 2020-04-03 | — | — | CN | disclosed |