Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20293630 | 0.85 | SMN1; SMN2 (0.60) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL15218062 | 0.81 | BLM (0.73) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL14547348 | 0.81 | BLM (0.73) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL21303540 | 0.78 | HSD17B10 (0.71) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL4457891 | 0.77 | BLM (0.47) | BLMSMN1; SMN2HPGDKMT2ATDP1 | |
| SCHEMBL13205216 | 0.76 | BLM (0.47) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL27880060 | 0.75 | BLM (0.46) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL15314315 | 0.75 | ALDH1A1 (0.46) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL12659218 | 0.74 | BLM (0.53) | BLMSMN1; SMN2HIF1AHPGDKMT2A | |
| SCHEMBL7716562 | 0.74 | BLM (0.44) | BLMSMN1; SMN2HIF1AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111150851-A | Ligand-cytotoxic drug conjugate, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2020-05-15 | — | — | CN | disclosed |