Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342965 | 0.84 | SMN1; SMN2 (0.53) | BLMSMN1; SMN2ALDH1A1RECQLLMNA | |
| SCHEMBL9079706 | 0.80 | LDHA (0.54) | SMN1; SMN2CTBP2NPC1RAB9AIDO1 | |
| SCHEMBL4457891 | 0.80 | BLM (0.47) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL15314315 | 0.78 | ALDH1A1 (0.46) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL15218062 | 0.77 | BLM (0.73) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL14547348 | 0.77 | BLM (0.73) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL13519211 | 0.76 | SMN1; SMN2 (0.43) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL11529482 | 0.76 | PPARA (0.49) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL28392004 | 0.74 | BLM (0.50) | BLMHPGDSMN1; SMN2CTBP2SRD5A2 | |
| SCHEMBL27721177 | 0.74 | OPRM1 (0.44) | BLMNPC1RAB9ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218098-A1 | MATRICES OF PROBES AND THEIR PREPARATION | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017670-A1 | MATRICES OF PROBES AND THEIR PREPARATION | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2001-03-15 | — | — | WO | disclosed |