Hexane

Hexane

SCHEMBL28393141

CCCCCC.COc1cc(C)cc(OC)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
PTGS2 P35354 1/20 0.48
AHR P35869 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
ACHE P22303 2/20 0.43
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
CYP3A4 P08684 2/20 0.39
POLB P06746 2/20 0.39
CNR2 P34972 2/20 0.39
ELANE P08246 1/20 0.38
KMT2A Q03164 1/20 0.38
PTPN1 P18031 1/20 0.38
ALOX5 P09917 1/20 0.38
CNR1 P21554 1/20 0.38
KDM4E B2RXH2 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16951162 0.87 AHR (0.57) ALDH1A1PTGS2AHRCNR2ELANE
SCHEMBL12501 0.84 ALDH1A1 (0.73) ALDH1A1PTGS2AHRACHECYP1A1
SCHEMBL8229999 0.82 PTGS2 (0.65) PTGS2GPR84CYP3A4CNR2ALOX5
SCHEMBL13095984 0.80 AHR (0.46) ALDH1A1AHRACHEELANETP53
SCHEMBL14461578 0.79 ESR1 (0.52) ALDH1A1AHRACHECYP1A1CYP1B1
SCHEMBL14848719 0.79 AHR (0.58) ALDH1A1PTGS2AHRCNR2CNR1
SCHEMBL21388518 0.79 PLA2G2A (0.56) ALDH1A1CNR2CNR1TP53ALOX15
SCHEMBL145855 0.79 ALDH1A1 (0.62) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL1171756 0.77 PTGS2 (0.76) ALDH1A1PTGS2GPR84CYP3A4CNR2
SCHEMBL28360552 0.77 PLA2G2A (0.59) ALDH1A1AHRCNR2CNR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110720456-B Application of 3, 5-dimethoxytoluene 西南林业大学 2021-11-16 CN disclosed
CN-110720456-A Application of 3, 5-dimethoxytoluene 西南林业大学 2020-01-24 CN disclosed