Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | VCP | P55072 | 1/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497323 | 0.95 | JUN (0.71) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28541317 | 0.92 | JUN (0.66) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30964227 | 0.92 | JUN (0.66) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8153885 | 0.91 | KDM4E (0.75) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8153880 | 0.91 | KDM4E (0.75) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30560923 | 0.91 | KDM4E (0.75) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28422571 | 0.90 | KDM4E (0.65) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18270549 | 0.89 | JUN (0.79) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| Acetamide SCHEMBL10706949 | 0.89 | KDM4E (0.78) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3207347 | 0.88 | NFKB1 (1.00) | JUNNFKB1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153898-B | Thiourea derivative and preparation method and application thereof | 南华大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111153898-A | Thiourea derivative and preparation method and application thereof | 南华大学 | 2020-05-15 | — | — | CN | disclosed |